British Air Force Typhoon jets have joined forces with France's air force in a joint strike against an subterranean weapons facility in Syria used by the IS group, per a report from the UK Ministry of Defence.
The facility, identified by intelligence, was believed to be housing weapons and explosive materials, the statement said, and was situated in mountainous terrain just above the historic site of Palmyra in central Syria.
"Our aircraft used laser-guided Paveway IV weapons to target a several entry passages leading to the facility... early reports indicate the target was engaged successfully," the MoD said.
There was no indication of any civilian impact in the strike on Saturday evening and all the aircraft returned to base without incident, the MoD added.
The Typhoon fighters were backed up by a Voyager refuelling tanker.
IS - alternatively referred to as Daesh - established jihadist rule over parts of Iraq and Syria until 2019.
"This operation shows our UK leadership, and determination to work closely with our allies, to stamp out any re-emergence of IS and their dangerous and violent ideologies in the area," Britain's Defence Chief John Healey said.
UK warplanes have carried out surveillance missions over Syrian airspace to "prevent any attempted resurgence" of Islamic State after its defeat at the Baghuz confrontation in the year 2019, the MoD reported.
"I extend gratitude to every member of the UK armed forces involved in this mission for their skill and their valour," Healey said. "They were part of numerous British troops on duty over the holidays. This operation, to take out militants who endanger our way of life, demonstrates how UK forces are always on standby, throughout the year, keeping Britain secure at home and strong abroad."
In December, the American forces conducted what it called a "large-scale strike" targeting Daesh sites in the country, subsequent to an ambush claimed the lives of two US servicemembers and a local interpreter in Palmyra.
The U.N. says IS still boasts roughly 5-7 thousand fighters in both countries.